Zinc Homeostasis in Platelet-Related Diseases
نویسندگان
چکیده
منابع مشابه
Platelet Septic Transfusion Reactions in Patients With Hemato-Oncological Diseases
Background & Objective: Bacterial, contamination of blood components are a significant risk for transfusion reactions. Inherently, platelet concentrates (PCs) are vulnerable to bacterial contamination, due to the storage condition of processed PCs at room temperature, which provide very suitable conditions for the proliferation of microorganisms....
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Zinc is an essential trace element, whose importance to the function of the central nervous system (CNS) is increasingly being appreciated. Alterations in zinc dyshomeostasis has been suggested as a key factor in the development of several neuropsychiatric disorders. In the CNS, zinc occurs in two forms: the first being tightly bound to proteins and, secondly, the free, cytoplasmic, or extracel...
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Transition metals such as Fe, Zn, and Cu are essential to plants but toxic in excess, and their accumulation is tightly regulated (Palmer and Guerinot, 2009). Offering exciting possibilities for applications such as bioremediation of contaminated sites and biofortification against nutritional deficiencies (e.g., of Zn; Palmgren et al., 2008), the molecular mechanisms of metal homeostasis are be...
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Pseudomonas aeruginosa is a ubiquitous environmental bacterium and a clinically significant opportunistic human pathogen. Central to the ability of P. aeruginosa to colonise both environmental and host niches is the acquisition of zinc. Here we show that P. aeruginosa PAO1 acquires zinc via an ATP-binding cassette (ABC) permease in which ZnuA is the high affinity, zinc-specific binding protein....
متن کاملEndogenous Zinc in Neurological Diseases
The use of zinc in medicinal skin cream was mentioned in Egyptian papyri from 2000 BC (for example, the Smith Papyrus), and zinc has apparently been used fairly steadily throughout Roman and modern times (for example, as the American lotion named for its zinc ore, 'Calamine'). It is, therefore, somewhat ironic that zinc is a relatively late addition to the pantheon of signal ions in biology and...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2019
ISSN: 1422-0067
DOI: 10.3390/ijms20215258